Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines
Lerner, Edwina C, Zhang, Ting-Ting, Knowles, David B, Qian, Yimin, Hamilton, Andrew D, Sebti, Saïd MТом:
15
Рік:
1997
Мова:
english
Сторінки:
6
DOI:
10.1038/sj.onc.1201296
Файл:
PDF, 406 KB
english, 1997