Simulation of human plasma concentration–time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite using humanized chimeric mice and semi-physiological pharmacokinetic modeling
Kamimura, Hidetaka, Ito, Satoshi, Chijiwa, Hiroyuki, Okuzono, Takeshi, Ishiguro, Tomohiro, Yamamoto, Yosuke, Nishinoaki, Sho, Ninomiya, Shin-Ichi, Mitsui, Marina, Kalgutkar, Amit S., Yamazaki, HiroshiМова:
english
Журнал:
Xenobiotica
DOI:
10.1080/00498254.2016.1199063
Date:
July, 2016
Файл:
PDF, 832 KB
english, 2016
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