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Volume 1; Issue 21

Organic & Biomolecular Chemistry

Volume 1; Issue 21
12

Development of two processes for the synthesis of bridged azabicyclic systems: intermolecular radical addition?homoallylic rearrangements leading to 2-azanorborn-5-enes and neophyl-type radical rearrangements to 2-azabenzonorbornanesThis is one of a number of contributions from the current members of the Dyson Perrins Laboratory to mark the end of almost 90 years of organic chemistry research in that building, as all its current academic staff move across South Parks Road to a new purpose-built laboratory.Electronic supplementary information (ESI) available: the preparation and characterisation of compounds 20b?i, 28c?g, 30b?g, 30i, 32e?g, 32i, 33b?g. See http//www.rsc.org/suppdata/ob/b3/b306717n/

Hodgson, David M., Bebbington, Magnus W. P., Willis, Paul
Журнал:
Organic & Biomolecular Chemistry
Рік:
2003
Мова:
english
Файл:
PDF, 276 KB
english, 2003
19

Ene cyclisations of ?-(prenyl)dialkylsilyloxy aldehydes: formation and oxidative cleavage of oxasilacyclohexanolsThis is one of a number of contributions from the current members of the Dyson Perrins Laboratory to mark the end of almost 90 years of organic chemistry research in that building, as all its current academic staff move across South Parks Road to a new purpose-built laboratory.Electronic supplementary information (ESI) available: spectroscopic data for compounds 1?4, and procedures with supporting characterisation for compounds 11, 21, 24, 25, 26 and 29. See http://www.rsc.org/suppdata/ob/b3/b306922m/

Robertson, Jeremy, Hall, Michael J., Stafford, Petra M., Green, Stuart P.
Журнал:
Organic & Biomolecular Chemistry
Рік:
2003
Мова:
english
Файл:
PDF, 231 KB
english, 2003
21

The Dyson Perrins Laboratory at Oxford

Журнал:
Organic & Biomolecular Chemistry
Рік:
2003
Мова:
english
Файл:
PDF, 143 KB
english, 2003
23

Synthesis of potent CXCR4 inhibitors possessing low cytotoxicity and improved biostability based on T140 derivativesElectronic supplementary information (ESI) available: Fig. S1: behaviors of TE14005 (a), TE14011 and Ac-TE14011 (b) in mouse serum; Fig. S2: behaviors of TE14011 (a), Ac-TE14011 (b), TN14003 (c), Ac-TN14003 (d), TC14012 (e) and Ac-TC14012 (f) in rat liver homogenate; Table S1: characterization data of novel synthetic peptides; HPLC charts for synthetic compounds of TE14005, TE14011 and Ac-TE14011, and for a degraded sample of TE14011 in rat liver homogenate and its co-injection with an authentic compound des-[Arg1, Arg2, Nal3]-TE14011. See http://www.rsc.org/suppdata/ob/b3/b306473p/

Tamamura, Hirokazu, Hiramatsu, Kenichi, Kusano, Shuichi, Terakubo, Shigemi, Yamamoto, Naoki, Trent, John O., Wang, Zixuan, Peiper, Stephen C., Nakashima, Hideki, Otaka, Akira, Fujii, Nobutaka
Журнал:
Organic & Biomolecular Chemistry
Рік:
2003
Мова:
english
Файл:
PDF, 205 KB
english, 2003
29

Enhancement of the T140-based pharmacophores leads to the development of more potent and bio-stable CXCR4 antagonistsElectronic supplementary information (ESI) available: Fig. S1: behaviors of TF14013, TF14016 and TF14013-Me in mouse serum; Fig. S2: behaviors of TF14002 (a), TF14005 (b), TF14006 (c), TF14013 (d), TF14016 (e) and TF14013 analogs (f) in rat liver homogenate; Table S1: characterization data of novel synthetic peptides; and HPLC charts for synthetic compounds of 4F-benzoyl-TE14011 (TF14013), 4F-benzoyl-TN14003 (TF14016), nicotinoyl-TE14011 (TF14031) and 4F-benzoyl-TE14011-Me (TF14013-Me), and for a degraded sample of 4F-benzoyl-TE14011 (TF14013) in rat liver homogenate and its co-injection with an authentic compound des-[Arg14-

Tamamura, Hirokazu, Hiramatsu, Kenichi, Mizumoto, Makiko, Ueda, Satoshi, Kusano, Shuichi, Terakubo, Shigemi, Akamatsu, Miki, Yamamoto, Naoki, Trent, John O., Wang, Zixuan, Peiper, Stephen C., Nakashim
Журнал:
Organic & Biomolecular Chemistry
Рік:
2003
Мова:
english
Файл:
PDF, 224 KB
english, 2003