Пожертвування 15 вересня 2024 – 1 жовтня 2024 Про збір коштів

Volume 21; Issue 5

Bioorganic & Medicinal Chemistry

Volume 21; Issue 5

1

Synthesis and biological evaluation of novel 2,4-disubstituted quinazoline analogues as GPR119 agonists

Pham, Tuan-Anh N., Yang, Zunhua, Fang, Yuanying, Luo, Jun, Lee, Jongkook, Park, Haeil

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 450 KB

english, 2013

2

N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase

Novikov, Mikhail S., Valuev-Elliston, Vladimir T., Babkov, Denis A., Paramonova, Maria P., Ivanov, Alexander V., Gavryushov, Sergey A, Khandazhinskaya, Anastasia L., Kochetkov, Sergey N., Pannecouque,

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 780 KB

english, 2013

3

Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema

Inoue, Takayuki, Morita, Masataka, Tojo, Takashi, Yoshihara, Kousei, Nagashima, Akira, Moritomo, Ayako, Ohkubo, Mitsuru, Miyake, Hiroshi

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 1.02 MB

english, 2013

4

Synthesis of 5,7-disubstituted-4-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amines as microtubule inhibitors

Gangjee, Aleem, Kurup, Sonali, Smith, Charles D.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 756 KB

english, 2013

5

Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2,3-dioxygenase (IDO) inhibitors

Tanaka, Minoru, Li, Xin, Hikawa, Hidemasa, Suzuki, Takafumi, Tsutsumi, Katsuhiko, Sato, Masashi, Takikawa, Osamu, Suzuki, Hideharu, Yokoyama, Yuusaku

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 733 KB

english, 2013

6

Whole-body imaging of tumor cells by azaelectrocyclization: Visualization of metastasis dependence on glycan structure

Tanaka, Katsunori, Moriwaki, Kenta, Yokoi, Satomi, Koyama, Koichi, Miyoshi, Eiji, Fukase, Koichi

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 573 KB

english, 2013

7

Evolvosides C–E, flavonol-4-O-triglycosides from Evolvulus alsinoides and their anti-stress activity

Gupta, Prasoon, Sharma, Upasana, Gupta, Praveen, Siripurapu, Kiran Babu, Maurya, Rakesh

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 383 KB

english, 2013

8

Synthesis of a 2,4,6-trisubstituted 5-cyano-pyrimidine library and evaluation of its immunosuppressive activity in a Mixed Lymphocyte Reaction assay

Stella, Alessandro, Van Belle, Kristien, De Jonghe, Steven, Louat, Thierry, Herman, Jean, Rozenski, Jef, Waer, Mark, Herdewijn, Piet

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 380 KB

english, 2013

9

Alkaloids from Sri Lankan curry-leaf (Murraya koenigii) display melanogenesis inhibitory activity: Structures of karapinchamines A and B

Nakamura, Seikou, Nakashima, Souichi, Oda, Yoshimi, Yokota, Nami, Fujimoto, Katsuyoshi, Matsumoto, Takahiro, Ohta, Tomoe, Ogawa, Keiko, Maeda, Sayuri, Nishida, Shino, Matsuda, Hisashi, Yoshikawa, Masa

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 491 KB

english, 2013

10

Secondary amines containing one aromatic nitro group: Preparation, nitrosation, sustained nitric oxide release, and the synergistic effects of released nitric oxide and an arginase inhibitor on vascular smooth muscle cell proliferation

Curtis, Brandon, Payne, Thomas J., Ash, David E., Mohanty, Dillip K.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 1.77 MB

english, 2013

11

Antiparkinsonian activity of some 9-N-, O-, S- and C-derivatives of 3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol

Ardashov, Oleg V., Pavlova, Alla V., Korchagina, Dina V., Volcho, Konstantin P., Tolstikova, Tat’yana G., Salakhutdinov, Nariman F.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 320 KB

english, 2013

12

Synthesis, biological evaluation and molecular modeling of aloe-emodin derivatives as new acetylcholinesterase inhibitors

Shi, Da-Hua, Huang, Wei, Li, Chao, Wang, Ling-Ting, Wang, Shi-Fan

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 2.07 MB

english, 2013

13

Polyamino geranic derivatives as new chemosensitizers to combat antibiotic resistant Gram-negative bacteria

Brunel, Jean Michel, Lieutaud, Aurélie, Lome, Vincent, Pagès, Jean-Marie, Bolla, Jean-Michel

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 450 KB

english, 2013

14

Synthesis and biological evaluation of enantiomerically pure cyclopropyl analogues of combretastatin A4

Ty, Nancy, Pontikis, Renée, Chabot, Guy G., Devillers, Emmanuelle, Quentin, Lionel, Bourg, Stéphane, Florent, Jean-Claude

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 1.24 MB

english, 2013

15

N2-Trimethylacetyl substituted and unsubstituted-N4-phenylsubstituted-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines: Design, cellular receptor tyrosine kinase inhibitory activities and in vivo evaluation as antiangiogenic, antimetastatic and antitumor agents

Gangjee, Aleem, Namjoshi, Ojas A., Yu, Jianming, Ihnat, Michael A., Thorpe, Jessica E., Bailey-Downs, Lora C.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 660 KB

english, 2013

16

9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro

Krečmerová, Marcela, Jansa, Petr, Dračínský, Martin, Sázelová, Petra, Kašička, Václav, Neyts, Johan, Auwerx, Joeri, Kiss, Eleonóra, Goris, Nesya, Stepan, George, Janeba, Zlatko

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 993 KB

english, 2013

17

Selective inhibition of glycosyltransferases by bivalent imidazolium salts

Gao, Yin, Vlahakis, Jason Z., Szarek, Walter A., Brockhausen, Inka

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 278 KB

english, 2013

18

Potent BRAF kinase inhibitors based on 2,4,5-trisubstituted imidazole with naphthyl and benzothiophene 4-substituents

Niculescu-Duvaz, Dan, Niculescu-Duvaz, Ion, Suijkerbuijk, Bart M.J.M., Ménard, Delphine, Zambon, Alfonso, Davies, Lawrence, Pons, Jean-Francois, Whittaker, Steven, Marais, Richard, Springer, Caroline

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 3.23 MB

english, 2013

19

New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA

Buchlovič, Marian, Kříž, Zdeněk, Hofr, Ctirad, Potáček, Milan

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 578 KB

english, 2013

20

Design, modification and 3D QSAR studies of novel naphthalin-containing pyrazoline derivatives with/without thiourea skeleton as anticancer agents

Yang, Wen, Hu, Yang, Yang, Yu-Shun, Zhang, Fei, Zhang, Yan-Bin, Wang, Xiao-Liang, Tang, Jian-Feng, Zhong, Wei-Qing, Zhu, Hai-Liang

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 1.55 MB

english, 2013

21

Naphthalenyl derivatives for hitting P-gp/MRP1/BCRP transporters

Colabufo, Nicola A., Contino, Marialessandra, Cantore, Mariangela, Capparelli, Elena, Perrone, Maria Grazia, Cassano, Giuseppe, Gasparre, Giuseppe, Leopoldo, Marcello, Berardi, Francesco, Perrone, Rob

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 586 KB

english, 2013

22

Evaluation of adamantane hydroxamates as botulinum neurotoxin inhibitors: Synthesis, crystallography, modeling, kinetic and cellular based studies

Šilhár, Peter, Silvaggi, Nicholas R., Pellett, Sabine, Čapková, Kateřina, Johnson, Eric A., Allen, Karen N., Janda, Kim D.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 828 KB

english, 2013

23

Design, synthesis and structure–activity relationship of novel tricyclic benzimidazolone derivatives as potent 18kDa translocator protein (TSPO) ligands

Fukaya, Takayuki, Kodo, Toru, Ishiyama, Takeo, Nishikawa, Hiroyuki, Baba, Satoko, Masumoto, Shuji

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 776 KB

english, 2013

24

Towards new boron carriers for boron neutron capture therapy: Metallacarboranes bearing cobalt, iron and chromium and their cholesterol conjugates

Białek-Pietras, Magdalena, Olejniczak, Agnieszka B., Tachikawa, Shoji, Nakamura, Hiroyuki, Leśnikowski, Zbigniew J.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 510 KB

english, 2013

25

Anticonvulsant evaluation of aminoalkanol derivatives of 2- and 4-methylxanthone

Szkaradek, Natalia, Gunia, Agnieszka, Waszkielewicz, Anna M., Antkiewicz-Michaluk, Lucyna, Cegła, Marek, Szneler, Edward, Marona, Henryk

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 1002 KB

english, 2013

26

Nebulosides A–B, novel triterpene saponins from under-ground parts of Gypsophila arrostii Guss. var. nebulosa

Arslan, Idris, Celik, Ali, Melzig, Matthias F.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 288 KB

english, 2013

27

Synthesis and mechanistic studies of novel spin-labeled combretastatin derivatives as potential antineoplastic agents

Liu, Ying-Qian, Li, Xiao-Jing, Zhao, Chun-Yan, Nan, Xiang, Tian, Jing, Morris-Natschke, Susan L., Zhang, Zhi-Jun, Yang, Xiao-Ming, Yang, Liu, Li, Lin-Hai, Zhou, Xing-Wen, Lee, Kuo-Hsiung

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 1.01 MB

english, 2013

28

Cyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthase

Li, Huiying, Xue, Fengtian, Kraus, James M., Ji, Haitao, Labby, Kristin Jansen, Mataka, Jan, Delker, Silvia L., Martásek, Pavel, Roman, Linda J., Poulos, Thomas L., Silverman, Richard B.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 1.55 MB

english, 2013

29

Identification of small-molecule inhibitors of the human S100B–p53 interaction and evaluation of their activity in human melanoma cells

Yoshimura, Chihoko, Miyafusa, Takamitsu, Tsumoto, Kouhei

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 832 KB

english, 2013

30

Publisher’s Note

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 182 KB

english, 2013

31

Mechanistic studies of the inactivation of tyrosinase by resorcinol

Stratford, Michael R.L., Ramsden, Christopher A., Riley, Patrick A.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 726 KB

english, 2013

32

Corrigendum to “The biology and chemistry of antifungal agents: A review” [Bioorg. Med. Chem. 20 (2012) 5678–5698]

Kathiravan, Muthu K., Salake, Amol B., Chothe, Aparna S., Dudhe, Prashik B., Watode, Rahul P., Mukta, Maheshwar S., Gadhwe, Sandeep

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 138 KB

english, 2013

33

Graphical contents list

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 2.01 MB

english, 2013

34

Synthesis and evaluation as potential anticancer agents of novel tetracyclic indenoquinoline derivatives

Chakrabarty, Shubhashis, Croft, Michael S., Marko, Melissa G., Moyna, Guillermo

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 314 KB

english, 2013

35

Editorial board

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 43 KB

english, 2013

36

The effect of absolute configuration on activity, subtype selectivity (M3/M2) of 3α-acyloxy-6β-acetoxyltropane derivatives as muscarinic M3 receptor antagonists

Wang, Zhi-Peng, Liu, Hui-Zhong, Zhu, Liang, Hu, You-Min, Cui, Yong-Yao, Niu, Yin-Yao, Lu, Yang, Chen, Hong-Zhuan

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 490 KB

english, 2013

37

Retrospective group fusion similarity search based on eROCE evaluation metric

Avram, Sorin I., Crisan, Luminita, Bora, Alina, Pacureanu, Liliana M., Avram, Stefana, Kurunczi, Ludovic

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 1.71 MB

english, 2013

38

Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA

Kaur, Moninderpal, Rupasinghe, Chamila N., Klosi, Edvin, Spaller, Mark R., Chow, Christine S.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 727 KB

english, 2013

39

Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a carbamoyl linker

Kokosza, Kamil, Balzarini, Jan, Piotrowska, Dorota G.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 496 KB

english, 2013

40

Incorporation of β-amino acids into dihydrofolate reductase by ribosomes having modifications in the peptidyltransferase center

Maini, Rumit, Nguyen, Dan T., Chen, Shengxi, Dedkova, Larisa M., Chowdhury, Sandipan Roy, Alcala-Torano, Rafael, Hecht, Sidney M.

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2013

Мова:

english

Файл:

PDF, 811 KB

english, 2013